National Kidney Foundation Primer on Kidney Diseases: Expert Consult - Online and Print, 6th Edition

The National Kidney Foundation Primer on Kidney Diseases is your ideal companion in clinical nephrology! From anatomy, histology, and physiology, through the diagnosis and management of kidney disease, fluid and electrolyte disorders, hypertension, dialysis, and kidney transplantation, this trusted manual from Elsevier and the National Kidney Foundation provides an accessible, efficient overview of kidney diseases that’s perfect for residency, fellowship, clinical practice, and board review.

- Incorporate the latest NKF Kidney/ Outcome Quality Initiative guidelines on chronic kidney disease staging and management.
- Review the basics with a current and practical review of the anatomy, physiology, pathophysiology, diagnosis, and management of kidney disease, fluid and electrolyte disorders, hypertension, dialysis, and renal transplantation.
- Put the latest knowledge to work in your practice with 8 brand-new chapters including kidney development,
assessment of kidney function in acute and chronic settings, the kidney in malignancy, acute tubular injury and acute tubular
necrosis, acute interstitial nephritis, Fabry Disease, immunosuppression, and transplant infectious disease, as well as
comprehensive updates on acute kidney injury, transplant medicine, kidney function and kidney disease in the
elderly, GFR estimation, biomarkers in kidney disease, recently described pathologic targets in membranous nephropathy,
minimal change disease, viral nephropathies, and much more!
- Get expert advice from a new team of editors, led by Scott Gilbert and Dan Weiner from Tufts University
School of Medicine, each bringing a fresh perspective and a wealth of clinical experience.
- Quickly access the complete contents online at Expert Consult, with fully searchable text, downloadable
images, and additional figures and graphs.

Table of Contents

Section 1: Structure and Function of the Kidneys and Their Clinical Assessment

Overview of Kidney Function and Structure
Kidney Development
Assessment of Glomerular Filtration Rate in Acute and Chronic Settings
Urinalysis and Urine Microscopy
Hematuria and Proteinuria
Kidney Imaging
Section 2: Acid-Base, Fluid, and Electrolyte Disorders

Hyponatremia and Hypoosmolar Disorders
Hypernatremia
Edema and the Clinical Use of Diuretics
Disorders of Potassium Metabolism
Disorders of Mineral Metabolism: Calcium, Phosphorus, and Magnesium
Approach to Acid-Base Disorders
Metabolic Acidosis
Metabolic Alkalosis
Respiratory Acidosis and Alkalosis
Section 3: Glomerular Diseases

Glomerular Clinicopathologic Syndromes
Minimal Change Disease
Focal Segmental Glomerulosclerosis
Membranous Nephropathy
Immunoglobulin A Nephropathy and Related Disorders
Goodpasture Syndrome and Other Antiglomerular Basement Membrane Diseases
Section 4: The Kidney in Systemic Disease

Postinfectious Glomerulonephritis
Kidney Involvement in Systemic Vasculitis
Kidney Manifestations of Systemic Lupus Erythematosus
Pathogenesis, Pathophysiology and Treatment of Diabetic Nephropathy
Dysproteinemias and Amyloidosis
Thrombotic Microangiopathies
Viral Nephropathies: Human Immunodeficiency Virus, Hepatitis C Virus, and Hepatitis B Virus
Acute Cardiorenal Syndrome
Hepatorenal Syndrome and Other Liver-Related Kidney Diseases
The Kidney in Cancers
Section 5: Acute Kidney Injury

Pathophysiology of Acute Kidney Injury
Clinical Approach to the Diagnosis of Acute Kidney Injury
Acute Tubular Injury and Acute Tubular Necrosis
Acute Interstitial Nephritis
Management of Acute Kidney Injury
Section 6: Drugs and the Kidney

Kidney Disease Caused by Therapeutic Agents
Principles of Drug Therapy in Patients with Reduced Kidney Function
Section 7: Hereditary Kidney Disorders

Genetically Based Renal Transport Disorders
Sickle Cell Nephropathy
Polycystic and Other Cystic Kidney Diseases
Nephronophthisis and Medullary Cystic Kidney Disease
Alport Syndrome and Related Disorders
Fabry Disease
Section 8: Tubulointerstitial Nephropathies and Disorders of the Urinary Tract

Chronic Tubulointerstitial Disease
Obstructive Uropathy
Nephrolithiasis
Urinary Tract Infection & Pyelonephritis
Section 9: The Kidney in Special Circumstances

The Kidney in Infants and Children
The Kidney in Pregnancy
Kidney Disease in the Elderly
Section 10: Chronic Kidney Disease and Its Therapy

Pathophysiology of Chronic Kidney Disease
Staging and Management of Chronic Kidney Disease
Nutrition and Kidney Disease
Bone Disorders in Chronic Kidney Disease
Cardiac Function and Cardiovascular Disease in Chronic Kidney Disease
Anemia and Other Hematologic Complications of Chronic Kidney Disease
Section 11: Kidney Replacement Therapies: Dialysis and Transplantation

Hemodialysis
Peritoneal Dialysis
Outcomes of Kidney Replacement Therapies
Selection of Prospective Kidney Transplant Recipients and Donors
Posttransplantation Monitoring and Outcomes
Immunosuppression in Transplantation
Infectious Complications of Kidney Transplantation
Section 12: Hypertension

Pathogenesis of Hypertension
Evaluation and Management of Hypertension
Secondary Hypertension